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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b72e944b0bfc8f9ec3a9c5e662f02d980e9b952f49960c6d404a9fc831e50df4' 
  AND token = '+S+VPe8APh4vDVIxQEeXmi3LGQpOsaeFElwQhhVurOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}