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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f13c616681b52547d15f0acf92fc4d53942f38f0591af27db63f40278568c603' 
  AND token = 'ZRgA2dGl9MHNMdubhas722/eSM4mRHtplQOEZaoo+ec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}