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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd53fc8508d06dddad1dfdf2c30f03a68d5e70c32a51f02ae8245f4112a6674e' 
  AND token = 'K3uyki54FKuJ6h3a2n8b7QTNifx+fxrrwcFX9K3Ei1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}