SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7255e9d61c5dba55587fc15c8c9f2537a5b58853d89da1c7758f5e666d4732fe' 
  AND token = 'vWEmQ7eP+f+8YVBn1SiWTH1xwbUhin8ovL+7I4NXiHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}