SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8807d482152b0d81005c1a295666a73e624f24092ca9b2b3bb50f4ee6118a076' 
  AND token = '2R/MHb2hq/vcRgoENKjNlFpBZuXa8EEEE4NIJvWrskc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}