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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12caa91e372cbeea52b8305e4a36b93ab42001e3d508eb7a9a0dad17174c4f8d' 
  AND token = 'nkPUq9ChvatNslLeoMlluwx74tumbe++jiDmy/85Cs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}