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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea678921f03ae1c1cc883cce82a3abfbcceb9ee930c8c73b3105d95de6be2e43' 
  AND token = '4MjQnskPbV+Ecdef9gAVIfTEEM9AnMClOvLeZl1QOXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}