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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e37295a51a8b39834a9a8ba3ae7075942b3bfea09867104ab0197977bf006b78' 
  AND token = 'wcAOsFgLe/G3nn/ccu38ygM+SUuml8m5rH58Z51bXgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}