SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f626c3fd7f5d2f81ccb2e94f5c7835e0152e07f76199c49f9b4e8286462db18a' 
  AND token = 'nPJJi0zmJshFgIbqGXHxNNT5QhwjngYFBs9nw4sBcXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}