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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c6ccfc1f0d870877c6d0c5279fb99b10c5b215a7ba8362414690adc9793d521' 
  AND token = '+ZSu9oya+zx1VzFWEcPSv5MS7ILEj+PzxENbktNxO5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}