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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd49b15ae0d0ed25cb8bfa02f3b4305ce1e2d2538e14764aa86b7303e4eb617a' 
  AND token = 'uW27yHf2TiOxf20+qXDeJSKA6acmW6e531PAHk9Gses=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}