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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a81fde235049e4f292304d372d4009f55e10591692af7b215a5bd261f76dad09' 
  AND token = 'PxQjHhdbfqR9cNqYVhNE3c+mcshyS+fNpTXDX4wZeh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}