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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8ee1f37acd62d7a990bf0535ba811f6bb1c151f44640115ce3cdcd8f60db602' 
  AND token = '6dxg7OfmHnF4xmKV+EWZtB5WNKaLmNiEtNJKY3Z6ulw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}