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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f76fc717f5a74f3656e5ab749bda717a5adfae645b2d27981bf9240806d6c02' 
  AND token = '+7sNVf8CeWiuKXrz/5eN3zWZKDpmhOaVyfk+4S1S2as=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}