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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01c8d7168ac805b5cf292ce81490b249fb24209d24a6f0975576499fca1315ca' 
  AND token = 'NVjuA9scg+v1VRTm4EITfC5byURSsqye/YXX53NlEqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}