SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49fd58fef17111c3551d1e5a84dff6b4e159695ac9ed1f9747a3d9178003af07' 
  AND token = '3YPU+1Xy5EpR9GsM/5AEdacNsOcedPB2elVWFlp6N9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}