SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c0546ca422bb8699bd27197fe9dad411f0bdd66785827f98a4e0577b907716b' 
  AND token = 'o3R6QwfCP0la7F98yYVuABEsAb++xYozElOVvuVbiTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}