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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c398aab834888366c802f55af8316e3a9e0ee3752219a5a133d2929f17130e37' 
  AND token = 'QtRz/iJxxgP9JIx/EjbEL+8AfmcuwxZQ5gOZcU7C5Gw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}