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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ce2dbef72058af2576c272275528f33f26e12f5ca1e7e46b033471e8aaad2e6' 
  AND token = 'DE1d0Bn/vImU8n8jSRdwG4Qrlfssiov4HzRU2DWEZFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}