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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ae94f58e0e8f23dd4df7f2e973c3b81d5e28f340a672a6063f3b022c907041a' 
  AND token = 'uKjoBrJyNKv/gAIKTe/XeWEzvj6ZfHWRKw54ckk6b5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}