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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5b38c08fb0c76e858e0d4cb908321c8176adafea12557022a3ab7fb1f321eca' 
  AND token = 'PPI6HcRomSWoOA2JBaj3kpMpGK9wXNpAF5NjdvSzjjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}