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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a1d900c71af8be3092ba935e591df05c8309a47cab2d5cc3bb45449a06d1578' 
  AND token = 'paS6z7zhPCSQR9ziqvk2SCV/rxR1FQminZNNcChy+HU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}