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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cab80b995760bef3c6402b885dbeffbb45cc2aeb527bb318bd5d23a79404377a' 
  AND token = '+kf3zk/RLiaagUY0KaGd1DC2BwgDuE0Zsb+iHNOF9nk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}