SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '298427b4a8dee660b7030e2e53090eac472793f07f0d5d2a08d9f8c07d2db4ef' 
  AND token = 'Xgh0YHgn1mObjQrNRAQacfxnresYOp7tk0k/SMxNcG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}