SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c555f1142690628d349e5bc8ceecc4dc3a27d99b5fe3f304207f4ae4bb7a940e' 
  AND token = '3gwp6xJZL4TwgDx70+ACJdvVxO7378YwgEJcjy4pwj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}