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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f42e02b494f7bf126551756d04bf74f85c1a0f9d4f460690c58dfbe207ba2415' 
  AND token = 'hp0wbtcUEMnfldStaWo5Yna43/n4WHk43BzSNTgSYhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}