SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a45563d1eaffd54feeaa9f1fbbeb3d8eeeb2309a9a52505b479bc02146a9a8f' 
  AND token = 'N8fhPdq3dazZskDot+ItiiDMerSMtC6XkPwKCMeyscE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}