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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '164b68110728e36bf41c3f7449f9ad0073ad12c9dae4c9fe34630390f9421934' 
  AND token = 'cR7NVLU2LfbtEVQNI3pOcEYXyxK6DomWXHvh9IhjgSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}