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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8a66f3fd07664b0f2b3b7f31c0421607232642420dbc68272d1356cf4eadc37' 
  AND token = 'urQmpcPgcaacqrOKCV3qk9HzTMjctgsrGL/opp0/C5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}