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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd72521a1f6c508183d0f334548b1fd7994a3ba00dc85df7c4bc93eabab199337' 
  AND token = 'JuiS7uK0xF1KqtEpF68FSrCC9J0iMGACzP5yuTu0Skk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}