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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a397dc661c203ef4a498194d2b71f1a0c261434e20691fa10483e7ca3573077a' 
  AND token = 'wSSpsfTZbRLC0v56p9QcE3qEp/uvOxmBYxfcBQQr2cw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}