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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b894b9f08836ed5814cdc4f014c1a64fb70e32c608446a1e07625f764c7e5f81' 
  AND token = 'yiYZ8Zzm1inHvIq2IoOun1rWVJYE6kk8Ld18fOBuGws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}