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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52c6a7b280ab1fe1b87aa43481f281e49a5cb1be0b44d4d28035e97a3b87d7a3' 
  AND token = 'VCR6XYlbbBNs+/uhrUGCeMnI/zMD7BC3938buxi0eGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}