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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b6974f935ae22754b589abf729944dbf8109961bc561934954368326d4d9f9a' 
  AND token = 'ZK+9U4CZYf3W+8vyETeLQA/RYVgSQvDEKSfRPOnt0WE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}