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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f289149d5eaa4e64843511ce0381f5a62517cf6aee15258f4a67c2c372dbcad' 
  AND token = 'Nt8b2Goyun11a7qQlrGrTulH7Du9jvEdHo2ZKV7mHu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}