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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e230bf75eb6965c24d9879926c917a3fa09dc0fa065d8ac62d15cf463426723' 
  AND token = 'YskYA/dxcXDnT1+TJ2dD2a08TcIqTztwQjWMyjgjWo0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}