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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de9b63eaf3d09e48d25b9a77d5fee3f71ebfc1cc7812e5043452ee33aee4abd4' 
  AND token = 'JkgoEIG3w72v4MjC9T6dAptGa60lNA8ojcJaR/SZwEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}