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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b67b64e675e9dd646ec9eb2c12ba6a26d67d07fb8fa45d56e45089896b3e08c' 
  AND token = 'F76TxSawfJfn9UIXlm0Vh+ne8eoaUQ3XHEtaR2omSw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}