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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c8370da43b2fac69647aeddefde7881dc20da8a60baacbe339f9417ba26150c' 
  AND token = 'JQ0Gbp3TVGPeRb/PiVnju5RktQDGKdN1hP/1e/DVWGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}