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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d59e2859e7efaa85ea1a6ecb573790de2ea26315a7249234c3f39a3aeda7b7d' 
  AND token = 't+4p02GlVUabMRP/z607Z2dCWEFEfqzpCJCBY58l7p0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}