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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b280ae7355e826b7ec3108b35d4d75c62528a3e5596dfc3ac56022e25def507e' 
  AND token = 'k/gR//SuBsxPdmA/riNaMysKKhijpw5SKTazU2Cmv8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}