SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b146313d5b3fb2fc0eca5e86fa56caa70cb232cbd5b10c8eb9c24e01dcc4302' 
  AND token = '71wljS1edBoco1rx1TDn3sjEk+92ICYbTnZ2e9X2mtY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}