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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '812b5b714dc9b0b671ccbd4982cbce6f881434fde9732a180f4a9fa8a0196537' 
  AND token = 'MT4oWvBm7KTEENMwCze8cnyFd8zk3ljWrJPI54AaxqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}