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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4685e958cbe65d6fe806c0f03582a88c1cdadf39e774f63785c819a91e0fcd07' 
  AND token = 'mHVv74+f5uRPk4wV0IEqSH/AyXhIz5mawzPCUr36Euc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}