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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2c28266f897cb707d287945b8e443a0f278cf430499d029cc33bb534ac9c421' 
  AND token = 'Zt+CI6BuvhI9gtTnSRRh1+1QilvR+8OSlg/1ySnOqNI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}