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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8e76d05b8c242b219ac1d3843584602eb17df0bb9b60a7dd08b68d456fed6e0' 
  AND token = '41dTb8DKzAxmBbUgrN8Jv2PQ1pCJpJgbA7pzWAQOqGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}