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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f44eff49e2e907693d2015c927e9cccdf578dfb531da91bb21b5c7456662203e' 
  AND token = 'pb/G3cBwOqVAXlMCVj0ppd6tiQQ9r1K51W5alh95ogM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}