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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b82245be513e8e988b8c371c3633b80b214c7c5e83286ad488b7c3471e982a15' 
  AND token = 'DFvF0v+sJnhGx8dNiAvituMpfXmyD9Jr+yklJuLOyR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}