SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c32a38c6169b39e282c4d2c526f886c8ced6858f277092ddc959eb590c1f205' 
  AND token = 'uyRuenVLLKB/B8hOGEVX+9irMv+dKFf58vRBNMuLJiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}