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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f39a3996bfc976865b9f99775991aef281a2413a0e50e20a6c70c1951c6232e3' 
  AND token = 'l7oFH5nEuERPk+UT5wsZDZy1YAgWkRO0rah+GAaEw6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}